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    Posts Tagged ‘Indinavir’

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    Indinavir inhibited hiv replication by 95 at concentrations ranging from approximately 25 to 100 nmol l in vitro , and an additive or synergistic antiviral effect was demonstrated in most studies combining indinavir with other antiretroviral agents in cell culture.

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    Bromocriptine is extensively metabolized in the liver via cyp3a4; indinavir is a strong inhibitor of cyp3a4.

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    Indinavir should be used with caution in patients with hepatic disease, including cirrhosis.

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